Table 3 Plate safety test results for inactivation of EBOV/Mak by the 0.5% and 1% NaOCl concentrations.

From: Efficacy of microbicides for inactivation of Ebola–Makona virus on a non-porous surface: a targeted hygiene intervention for reducing virus spread

Test condition (contact time)

0.5% NaOCl

1% NaOCl

Trial 1

Trial 2

Trial 3

Trial 1

Trial 2

Trial 3

Negative control

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

N + NaOCl

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

Positive control

+, +, +

+, +, +

+, +, +

+, +, +

+, +, +

+, +, +

NaOCl (1 min)

+, +, +

+, +, +

+, +, +

+, +, +

+, +, +

+, +, +

NaOCl (2.5 min)

+, −, +

−, +, −

+, +, +

+, +, +

−, +, +

+, +, +

NaOCl (5 min)

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

NaOCl (7.5 min)

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

NaOCl (10 min)

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

−, −, −

  1. The Vero E6 cultures were inoculated with undiluted neutralized samples and passaged twice. +, viral CPE observed; −, viral CPE not observed, or no cytotoxicity observed for N + NaOCl (neutralizer + NaOCl cytotoxicity control) (modified from Cook et al.11).