Table 3 Unadjusted (uHR) and adjusted (aHR) Cox proportional hazard ratios and 95% confident intervals (CI) for mortality risk factors among 345 HIV-positive presumptive TB participants in whom TB was not documented after 2 years of follow-up.

From: Mortality and risk of tuberculosis among people living with HIV in whom TB was initially ruled out

Type of variable

Variable

44 HIV infected presumptive TB cases died

301 HIV infected presumptive TB cases alive

uHR

aHRa

nb

(%)c

nb

(%)c

(95% CI)

p value

(95% CI)

p value

Socio-demographic

Age

42

 

281

(%)

    

< 15

 

7.14

 

12.46

Ref

 

Ref

 

15–24

 

9.52

 

14.95

1.06 (0.24–4.75)

0.935

1.10 (0.24–4.97)

0.899

25–34

 

38.10

 

28.47

2.19 (0.64–7.53)

0.211

1.94 (0.55–6.77)

0.3

35–44

 

11.90

 

19.93

1.03 (0.25–4.31)

0.967

0.74 (0.16–3.23)

0.695

45–54

 

9.52

 

9.96

1.58 (0.35–7.01)

0.549

1.11 (0.22–5.54)

0.892

 > 55

 

23.81

 

14.23

2.62 (0.72–9.54)

0.143

2.65 (0.72–9.71)

0.139

Sex

44

 

301

     

Female

 

56.82

 

58.80

Ref

 

Ref

 

Male

 

43.18

 

41.20

1.09 (0.60–1.99)

0.767

1.10 (0.61–1.99)

0.737

Occupation

38

 

269

     

Agriculture

 

34.21

 

44.24

Ref

 

Ref

 

Services

 

26.32

 

21.19

1.56 (0.69–3.55)

0.285

2.20 (0.83–5.83)

0.112

Student

 

0.00

 

2.97

NA

NA

NA

NA

No occupation

 

39.47

 

31.60

1.59 (0.76–3.35)

0.218

2.10 (0.93–4.71)

0.073

Marital status

40

 

274

     

Married

 

20.00

 

17.88

Ref

 

Ref

 

Union

 

25.00

 

29.93

0.77 (0.30–1.96)

0.583

0.80 (0.30–2.08)

0.646

Widower

 

2.50

 

8.03

0.28 (0.03–2.24)

0.233

0.26 (0.04–1.70)

0.162

Single

 

52.50

 

44.16

1.07 (0.47–2.43)

0.866

1.05 (0.46–2.40)

0.895

Number of people living in same house

40

 

278

     

From 0 to 3

 

52.5

 

34.53

Ref

 

Ref

 

From 4 to 6

 

32.5

 

44.96

0.50 (0.25–1.00)

0.051

0.60 (0.28–1.26)

0.179

7 or more

 

15

 

20.50

0.48 (0.20–1.17)

0.108

0.51 (0.21–1.28)

0.155

Health care access

Distance in Km from household to MDH

36

 

271

     

> 15

 

27.78

 

29.89

Ref

 

Ref

 

From 7.5 to 15

 

22.22

 

16.97

1.33 (0.53–3.33)

0.545

0.98 (0.33–2.90)

0.977

From 0 to < 7.5

 

50.00

 

53.14

1.00 (0.46–2.17)

0.999

1.02 (0.44–2.32)

0.97

Distance in Km from household to closest HCU

36

 

272

     

From 0 to < 5

 

91.67

 

90.07

Ref

 

Ref

 

From 5 to 10

 

5.56

 

8.82

0.65 (0.15–2.79)

0.57

0.68 (0.15–3.13)

0.617

> 10

 

2.78

 

1.10

2.05 (0.33–12.68)

0.439

2.08 (0.51–8.51)

0.309

TB transmission and care knowledge

TB transmission knowledge

(%)

41

 

280

     

Cough

 

85.37

 

75.36

Ref

 

Ref

 

At leat 1 missconception

 

0.00

 

3.21

NA

NA

NA

NA

Cough plus another TB symptom

 

14.63

 

21.43

NA

NA

NA

NA

TB treatment by traditional medicine

(%)

39

 

258

     

No

 

89.74

 

86.82

Ref

 

Ref

 

Yes

 

0.00

 

3.49

NA

NA

NA

NA

Do not know

 

10.26

 

9.69

1–05 (0.38–2.92)

0.922

1.11 (0.40–3.13)

0.837

  1. NA: Missing values for variables "Occupation", "TB transmission knowledge" and "TB treatment by traditional medicine" in the multivariable analysis.
  2. MDH: Manhiça District Hospital, HCU: Health care unit.
  3. aIn the Cox hazard regression analysis, adjustement was performed for the following variables: age, sex, previous episode of TB, having a family member with a previous episode of TB, and BCG vaccination.
  4. bn is sample size of variable specified.
  5. cResults are displayed in % if no other specification is provided.