Table 2 Median, 25th (p25), 75th (p75) percentiles and p values for between-group comparisons in RTD, limits of stability and striatal shape between individuals with pro-HD and HC.

From: Rate of torque development and striatal shape in individuals with prodromal Huntington's disease

 

Pro-HD Median (p25; p75)

HC Median (p25; p75)

p value

Relative RTD %MVC/s

1.41 [0.83; 2.59]

1.95 [1.21; 2.59]

0.159

Absolute RTD Nm/s

162.05 [69.16; 288.00]

178.83 [74.98; 231.08]

0.754

Left caudate a.u

−0.11 [−0.57; 0.07]

0.47 [−0.05; 0.63]

0.015

Right caudate a.u

−0.09 [−0.60; 0.08]

0.29 [0.01; 0.56]

0.001

Left putamen a.u

−0.06 [−0.53; 0.20]

0.17 [0.02; 0.31]

0.037

Right putamen a.u

−0.16 [−0.48; 0.10]

0.20 [0.07; 0.39]

0.001

Reaction time (ms)

0.79 [0.56; 0.9]

0.92 [0.74; 0.98]

0.224

Movement velocity (deg/s)

3.13 [2.46; 3.93]

3.32 [2.68; 3.71]

0.475

End point

Excursion (%)

55.25 [42.00; 61.75]

72.06 [64.87; 78.25]

0.000

Maximum excursion (%)

77.12 [66.12; 85.75]

90.37 [85.00; 93.12]

0.000

Directional control (%)

80.75 [78.37; 83.25]

74.37 [55.25; 81.37]

0.010

  1. pro-HD prodromal Huntington’s disease, HC healthy controls, RTD rate of torque development, MVC maximum voluntary contractions. Data are presented as median [Q1; Q3]. Results were considered significant at p < 0.05.