Table 2 Perioperative profiles of the study patients.

From: Video-assisted thoracoscopic lobectomy is feasible for selected patients with clinical N2 non-small cell lung cancer

Variables

Overall cohort

IPTW-adjusted cohort

VATS (n = 121)

Thoracotomy (n = 147)

p value

VATS (n = 121)

Thoracotomy (n = 147)

p value

Hospital days, days

7.3 ± 4.7

9.2 ± 4.4

0.001

7.7 ± 4.6

9.1 ± 4.2

0.028

Resection margins

  

0.079

  

0.488

R0

114 (94.2)

128 (87.1)

 

112 (92.6)

133 (90.5)

 

R1

7 (5.8)

19 (12.9)

 

9 (7.4)

14 (9.5)

 

Lymph node dissection

Lymph nodes harvested, n

31.6 ± 14.4

30.0 ± 10.0

0.634

31.9 ± 13.3

29.4 ± 9.6

0.100

Positive lymph nodes, n

4.7 ± 5.2

4.3 ± 5.9

0.316

4.6 ± 5.1

4.7 ± 5.9

0.980

Pathological tumor size

33.3 ± 12.1

36.7 ± 11.4

0.018

36.0 ± 12.1

35.3 ± 11.4

0.684

8th pathologic T factor

  

0.283

  

0.543

T1

35 (28.9)

31 (21.1)

 

25 (20.7)

40 (27.2)

 

T2

71 (58.7)

92 (62.6)

 

77 (63.6)

86 (58.5)

 

T3

15 (12.4)

24 (16.3)

 

19 (15.7)

21 (14.3)

 

8th pathologic N factor

  

0.365

  

0.847

N0

30 (24.8)

42 (28.6)

 

31 (25.6)

37 (25.2)

 

N1

8 (6.6)

16 (10.9)

 

8 (6.6)

13 (8.8)

 

 N1a

7 (5.8)

15 (10.2)

 

7 (5.8)

12 (8.1)

 

 N1b

1 (0.8)

1 (0.7)

 

1 (0.8)

1 (0.7)

 

N2

83 (68.6)

89 (60.5)

 

82 (67.8)

97 (66.0)

 

 N2a1

18 (14.9)

13 (8.8)

 

14 (11.6)

15 (10.2)

 

 N2a2

28 (22.3)

39 (26.5)

 

32 (26.4)

39 (26.5)

 

 N2b

38 (31.4)

37 (25.2)

 

36 (29.8)

43 (29.3)

 

8th pathologic stage

  

0.452

  

0.882

I

20 (16.5)

27 (18.4)

 

18 (14.9)

24 (16.3)

 

II

17 (14.0)

28 (19.0)

 

20 (16.5)

22 (15.0)

 

III

84 (69.4)

92 (62.6)

 

83 (68.6)

101 (68.7)

 

Adjuvant chemotherapy

65 (53.7)

77 (52.4)

0.924

66 (54.5)

69 (46.9)

0.287

Time to start chemotherapy, days

36.7 ± 18.1

43.4 ± 22.1

0.036

36.9 ± 14.3

43.1 ± 22.3

0.033

Adjuvant radiotherapy

55 (45.5)

68 (46.3)

0.993

56 (46.3)

66 (44.9)

0.829

  1. Data are presented as number (%) unless otherwise noted. IPTW inverse probability of treatment weighting; video-assisted thoracoscopic surgery, R0 completely resected tumor, R1 microscopic residual tumor.