Figure 5

Decision curve analysis for the bleeding risk nomogram. The y-axis measures the net benefit. The blue line represents the bleeding risk nomogram. The thin solid line represents the assumption that all patients were bleeding during the course of ITP progression. The thick solid line (parallel to the x-axis) represents the assumption that no patients were bleeding. The net benefit was calculated by subtracting the proportion of all patients who are false positive from the proportion who are true positive, weighting by the relative harm of forgoing treatment compared with the negative consequences of an unnecessary treatment. In this study, 14% (the intersection of blue line and thin solid line) was false positive rate and 88% (the intersection of blue line and thick solid line) was false negative rate.