Table 2 Anthropometric and sleep parameters related with active TGF-β1 serum levels in the non-obese and obese OSA patients.

From: Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma

 

Non-obese OSA patients

Obese OSA patients

r

95%CI

p

r

95%CI

p

Age (years)

0.013

− 0.168 to 0.193

0.887

0.301

0.053 to 0.514

0.018

BMI (Kg m−2)

0.020

− 0.161 to 0.200

0.828

− 0.029

− 0.279 to 0.224

0.825

Neck circumference (cm)

− 0.055

− 0.233 to 0.127

0.555

0.203

− 0.051 to 0.433

0.116

ESS

− 0.145

− 0.317 to 0.037

0.116

0.105

− 0.151 to 0.348

0.420

AHI (h−1)

0.241

0.063 to 0.404

0.008

0.225

− 0.028 to 0.451

0.081

DI (h−1)

0.215

0.036 to 0.381

0.025

0.059

− 0.196 to 0.306

0.651

Mean nocturnal SpO2 (%)

− 0.102

− 0.278 to 0.080

0.273

− 0.007

− 0.258 to 0.245

0.956

Low nocturnal SpO2 (%)

− 0.236

− 0.400 to − 0.058

0.014

− 0.067

− 0.314 to 0.188

0.605

tSpO2 < 90% (%)

0.208

0.028 to 0.375

0.045

0.085

− 0.170 to 0.330

0.512

Leptin serum levels (ng mL−1)

0.206

0.026 to 0.373

0.025

0.413

0.180 to 0.602

0.001

  1. BMI body mass index; ESS Epworth sleepiness score; AHI apnea–hypopnea index; DI desaturation index; SpO2 oxygen saturation; tSpO2 < 90% night time spent with oxygen saturation < 90%; r Spearman correlation coefficient; CI confidence interval.
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