Figure 3 | Scientific Reports

Figure 3

From: The S-nitrosylation of parkin attenuated the ubiquitination of divalent metal transporter 1 in MPP+-treated SH-SY5Y cells

Figure 3

GSNO and MPP+ increased NO generation in parkin-transfected SH-SY5Y cells. Changes of oxidized NO levels following different treatment (200 μM of MPP+; 200 μM of GSNO; 200 μM of GSNO + 1 mM of L-NNA) for 24 h in parkin-transfected SH-SY5Y cells. **P = 0.004, parkin-GSNO versus parkin-GSH; ^^^P = 0.0007, parkin-MPP+ versus parkin-NS; ###P = 0.0009, parkin-MPP+ + L-NNA versus parkin-MPP+. P = 0.063, parkin-MPP+ versus parkin-GSNO. N = 6.

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