Figure 1 | Scientific Reports

Figure 1

From: Novel diffuse white matter abnormality biomarker at term-equivalent age enhances prediction of long-term motor development in very preterm children

Figure 1

Objective segmentation of diffuse white matter abnormality (DWMA) in the centrum semiovale. The top three panels display raw axial T2-weighed MRI images through the centrum semiovale (immediately above the lateral ventricles) from very preterm infants born at 27 weeks (left), 26 weeks (center) and 31 weeks (right) gestation and imaged at term-equivalent age. Higher signal intensity than the subcortical white matter can be seen in the central white matter of the centrum semiovale, particularly for the 31-week gestation infant. The bottom panels display the corresponding slices with objectively segmented DWMA in yellow. The 27-week infant (left) was diagnosed with mild DWMA, the 26-week infant (center) was diagnosed with moderate DWMA, and the 31-week infant had severe DWMA.

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