Table 2 Regression coefficients for linear regression models of objectively quantified, normalized DWMA volume versus visually-classified DWMA as predictors of Bayley-III Motor composite score in very preterm infants.
Predictors | Univariate Relationship Coefficients (95% CI) | P | Multivariable Model Coefficients (95% CI) | P |
|---|---|---|---|---|
Adjusted R2: 25.8% | Adjusted R2: 41.1% | |||
DWMA volume* | −16.04 (−22.14, −9.95) | < 0.001 | −12.59 (−18.70, −6.48) | 0.001 |
Male sex | 1.88 (−2.45, 6.22) | 0.390 | ||
Gestational age | 1.28 (0.23, 2.33) | 0.017 | ||
Global brain abnormality score | −0.89 (−1.94, 0.16) | 0.097 | ||
Center/NICU | 1.23 (−0.90, 3.36) | 0.255 | ||
Postmenstrual age at MRI | −3.58 (−7.54, 0.38) | 0.076 | ||
Adjusted R2: 0.6% | Adjusted R2: 27.0% | |||
Visually-classified DWMA | 2.34 (−1.52, 6.22) | 0.232 | 0.70 (−2.92, 4.32) | 0.702 |
Male sex | 0.51 (−4.25, 5.29) | 0.831 | ||
Gestational age | 1.57 (0.41, 2.72) | 0.009 | ||
Global brain abnormality score | −1.56 (−2.68, −0.44) | 0.007 | ||
Center/NICU | 0.97 (−1.54, 3.48) | 0.445 | ||
Postmenstrual age at MRI | −2.06 (−6.51, 2.39) | 0.359 | ||
Adjusted R2: 20.9% | Adjusted R2: 27.9% | |||
Global brain abnormality score | −2.34 (−3.36, −1.33) | < 0.001 | −1.55 (−2.67, -0.44) | 0.007 |
Male sex | 0.49 (−4.25, 5.24) | 0.836 | ||
Gestational age | 1.58 (0.44, 2.73) | 0.008 | ||
Center/NICU | 1.13 (−1.23, 3.48) | 0.343 | ||
Postmenstrual age at MRI | −2.24 (−6.56, 2.09) | 0.306 |
