Figure 4

Gene networks combined by the common GSEA pathways. The GSEA results revealed significant transcriptional changes of several pathways involved in inflammatory responses in the L. tropica infected lesions, including “Chemokine receptors bind chemokines” , “Signaling by Interleukins”, “IL-10 signaling”, “IL-4 and IL-13 signaling” “IFN-γ signaling”, “IFN-α/β signaling”, and “IFN Signaling”, for UCL (a) and NUCL (b). This figure was created using Cytoscape version 3.7.2 and the Reactome FI plugin version 7.2.0.