Figure 2
AFM image and the effect of RGDV-gemcitabine on surface morphology of A549 cells: (a) AFM image of A549 cells in RPMI-1640 medium with 10% FBS, of which the surfaces are smooth and have no pseudopodia; (b) AFM image of A549 cells in RPMI-1640 medium without 10% FBS, the locally amplified illustration shows conical pseudopodia that are highlighted with red arrowhead and suggests that serum starvation A549 cells are able to extend pseudopodia; (c) AFM image of 0.5 μM of RGDV-gemcitabine treated A549 cells in serum starvation, of which the surfaces are smooth without pseudopodia and on the surface there are some nano-particles.
