Figure 3 | Scientific Reports

Figure 3

From: Exploring the action of RGDV-gemcitabine on tumor metastasis, tumor growth and possible action pathway

Figure 3

Effect of 0.5 μM of RGDV-gemcitabine on the migration, invasion, adhesion and monolayer of A549 cells: (a) effect of 0.5 μM of RGDV-gemcitabine on the migration of A549 cells, which shows that the migration cells induced by 0.5 μM of RGDV-gemcitabine are significantly lower than the migration cells induced by 0.5 μM of gemcitabine and PBS; (b) effect of 0.5 μM of RGDV-gemcitabine on the invasion of A549 cells, which shows that the invasion cells induced by 0.5 μM of RGDV-gemcitabine are significantly lower than the invasion cells induced by 0.5 μM of gemcitabine and PBS; (c) effect of 0.5 μM of RGDV-gemcitabine on the adhesion of A549 cells, which shows that the adhesion cells induced by 0.5 μM of RGDV-gemcitabine are significantly lower than the adhesion cells induced by 0.5 μM of gemcitabine and PBS; (d) effect of 0.5 μM of RGDV-gemcitabine on scratch width of A549 cell monolayer, showing that the potency of 0.5 μM of RGDV-gemcitabine decreasing the scratch width of A549 cell monolayer is significantly lower than those of 0.5 μM of gemcitabine and PBS decreasing the scratch width of A549 cell monolayer ; n = 3.

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