Figure 4
Quantification of lung [18F]F-FDG standard uptake ratio (SUR) and CT parameters: representative SUR data from a mouse quantified for each 5 min imaging time-frame (a–d) Percent (%) lung [18F]F-FDG SUR plotted against corresponding lung X-ray CT units (in arbitrary grey values), (e–h) Smoothened % lung [18F]F-FDG SUR plotted against the lung X-ray CT units (grey values), (i) three imaging time-frames were then pooled to plot the % Lung [18F]F-FDG at baseline, as well as 0, 24 and 28 h post-O3 exposure. (j) Regional lung mean, upper and lower range CT grey (arbitrary) values shown at baseline, as well as 0, 24 and 28 h post-O3 exposure. Baseline data is shown in blue, O3-0 h in red, O3-24 h in green and O3-28 h in purple scatter plots. Data from figures (i) and (j) were analysed by one-way ANOVA, * represents significance at p < 0.05 and ** at p < 0.01.
