Table 1 Clinical characteristics of the study subject.

From: FIB-4 index is a marker for a subsequent decrease in insulin secretion in a non-diabetic Japanese population

Characteristics

Cross-sectional

Longitudinal

p

Number (gender: M/F)

1268 (485/773)

439 (178/261)

0.577

Age (years)

51.4 ± 15.9

53.1 ± 13.7

0.051

Body mass index (kg/m2)

22.6 ± 3.4

22.5 ± 3.2

0.817

Fat (%)

24.7 ± 8.2

23.9 ± 7.7

0.073

Systolic blood pressure (mmHg)

127.0 ± 19.7

127.5 ± 18.9

0.639

Diastolic blood pressure (mmHg)

76.7 ± 11.9

77.6 ± 11.2

0.145

FIB-4 index

1.21 ± 0.70

1.22 ± 0.59

0.095

AST (IU/L)

22.4 ± 29.8

21.5 ± 7.1

0.538

ALT (IU/L)

20.5 ± 21.9

20.4 ± 13.3

0.892

γGTP

30.5 ± 38.8

28.4 ± 20.3

0.815

Blood pletelet count (109/L)

23.5 ± 5.6

23.2 ± 5.2

0.252

HbA1c (%)

5.62 ± 0.30

5.65 ± 0.34

0.059

Fasting plasma glucose (mg/dl)

80.6 ± 10.2

80.1 ± 9.1

0.328

Fasting serum insulin:IRI (mU/ml)

4.5 ± 2.6

4.2 ± 2.1

0.111

HOMA-R

0.90 ± 0.60

0.85 ± 0.46

0.265

HOMA-β

134.3 ± 167.8

123.7 ± 142.3

0.562

Serum albumin (g/dl)

4.5 ± 0.3

4.5 ± 0.3

0.432

LDL cholesterol (mg/dl)

115.9 ± 29.1

117.6 ± 28.1

0.283

Triglyceride (mg/dl)

94.2 ± 71.7

93.8 ± 64.2

0.902

HDL cholesterol (mg/dl)

65.2 ± 16.7

65.9 ± 17.1

0.437

Serum uric acid (mg/dl)

4.9 ± 1.4

4.9 ± 1.4

0.794

Serum urea nitrogen (mg/dl)

14.4 ± 4.3

14.7 ± 4.3

0.229

Serum creatinine (mg/dl)

0.69 ± 0.15

0.70 ± 0.16

0.914

Hypertension: n (%)

472 (37.2)

168 (38.3)

0.697

Hyperlipidemia: n (%)

356 (28.1)

130 (29.6)

0.539

Drinking alcohol: n (%)

568 (44.9)

223 (46.2)

0.618

Smoking (never/past/current): n

767/255/244

274/99/66

0.116

  1. Data are mean ± SD or number of subjects (%).