Table 2 Factors correlated with HOMA indices in the subjects of the cross sectional study.

From: FIB-4 index is a marker for a subsequent decrease in insulin secretion in a non-diabetic Japanese population

 

HOMA-β

HOMA-R

Univariate

Multivariate#

Univariate

Multivariate#

Characteristics

β

p

β

p

β

p

β

p

Gender (F)

0.124

 < 0.001

0.064

0.097

0.052

0.066

0.186

 < 0.001

Age (years)

− 0.405

< 0.001

− 0.151

0.003

0.030

0.288

0.085

0.073

Body mass index (kg/m2)

0.167

 < 0.001

–

–

0.496

 < 0.001

0.389

 < 0.001

Fat (%)

0.225

 < 0.001

0.200

 < 0.001

0.455

 < 0.001

–

–

Systolic blood pressure (mmHg)

− 0.163

 < 0.001

0.010

0.707

0.150

 < 0.001

–

–

Diastolic blood pressure (mmHg)

− 0.051

0.071

–

–

0.161

 < 0.001

0.040

0.115

FIB-4 index

− 0.445

 < 0.001

− 0.254

 < 0.001

− 0.131

 < 0.001

− 0.247

 < 0.001

AST (IU/L)

− 0.090

0.001

–

–

− 0.078

0.006

–

–

ALT (IU/L)

− 0.002

0.953

–

–

0.070

0.012

–

–

γGTP

− 0.056

0.046

0.067

0.024

0.102

 < 0.001

0.023

0.463

Blood pletelet count (109/L)

0.200

 < 0.001

–

–

0.072

0.011

–

–

HbA1c (%)

− 0.286

 < 0.001

− 0.184

 < 0.001

0.217

 < 0.001

0.129

 < 0.001

Serum albumin (g/dl)

0.093

 < 0.001

–

–

0.081

0.004

–

–

LDL cholesterol (mg/dl)

− 0.067

0.016

− 0.009

0.723

0.199

 < 0.001

0.005

0.847

Triglyceride (mg/dl)

0.113

 < 0.001

–

–

0.305

 < 0.001

0.184

 < 0.001

HDL cholesterol (mg/dl)

− 0.145

 < 0.001

− 0.122

 < 0.001

− 0.267

 < 0.001

–

–

Serum uric acid (mg/dl)

− 0.006

0.83

–

–

0.138

 < 0.001

0.062

0.043

Serum urea nitrogen (mg/dl)

− 0.266

 < 0.001

− 0.022

0.403

0.021

0.463

–

–

Serum creatinine (mg/dl)

− 0.046

0.098

–

–

0.039

0.167

–

–

Drinking alcohol: n (%)

− 0.126

 < 0.001

− 0.102

 < 0.001

− 0.149

 < 0.001

− 0.111

 < 0.001

Smoking (never/past/current): n

0.027

0.330

–

–

− 0.071

0.0120

− 0.057

0.030

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