Figure 3

Effects of paraoxon administration. The changes at each endpoint over time as a ratio to the control value for the Pox alone group. (a) Graph for preBötC amplitude, (b) graph for preBötC duration, (c) graph for preBötC frequency, (d) graph for XII amplitude, (e) graph for XII duration, (f) graph for XII frequency. Control: the 1-min mean of each item at the 20th min in the 2nd phase (Table 1) was calculated and defined as the control value. The control value was 100% when the ratio was calculated according to the change over time. Pmax: the values for the maximum effect were defined as burst amplitude, duration, and frequency. The most decline in mean burst amplitude per min occurred at 20 min of paraoxon administration (3rd phase in Table 1). This value was expressed as a ratio relative to the control value. Pend: Paraoxon was perfused for 20 min. The 1-min mean of each endpoint at the 20th minute (the last 1 min of the 3rd phase in Table 1) was calculated and expressed as a ratio relative to the control value. Last: rACSF was perfused for 20 min because of wash out (4th phase in Table 1). The mean of each parameter per min at the 20th min was calculated and expressed as a ratio relative to the control value. *Statistically significant differences by one-way ANOVA and Bonferroni analysis (p < 0.05).