Figure 4

Results related to therapeutic intervention and physostigmine administration. The results of the value for the maximum effect of each item relative to that of the control as a ratio for the 4 groups presented in Table 1. (a) Graph for preBötC amplitude, (b) graph for preBötC duration, (c) graph for preBötC frequency, (d) graph for XII amplitude, (e) graph for XII duration, (f) graph for XII frequency. Control: the 1-min mean of each item at the 20th min in the 1st or 2nd phase (Table 1) was calculated for each group and defined as the control value. The control value was 100% when the ratio was calculated according to the change over time. Pox alone: the value for the maximum effect in the 3rd phase (Table 1) in the Pox alone group was expressed as a ratio relative to the control value. Physo: The value for the maximum effect in the 3rd phase (Table 1) of physostigmine administration was expressed as a ratio relative to the control value. Pre: The value for the maximum effect in the 3rd phase (Table 1) for the pre-treatment group was expressed as a ratio relative to the control value. Sim: The value for the maximum effect value in the 3rd phase (Table 1) for the simultaneous treatment group was expressed as a ratio relative to the control value. Post: The value for the maximum effect in the 3rd phase (Table 1) in the post-treatment group was expressed as a ratio relative to the control value. *Statistically significant differences by one-way ANOVA and Bonferroni analysis (p < 0.05). ^†Statistically significant differences by F test and unpaired t test (p < 0.05).