Table 1 Clinical and immunological data for patients with septic shock.
Septic shock patients (n = 30) | |
|---|---|
Admission data | |
Sex, male, n (%) | 21 (70) |
Median age, years [IQR] | 66 [59–73] |
Median BMI, kg/m2 [IQR] | 27 [21–34] |
Median SAPS II [IQR] | 59 [48–77] |
Median SOFA score (day 1) [IQR] | 8 [7–10] |
Median plasma lactate level, mM [IQR] | 3.2 [2.6–5.2] |
Median CCI [IQR] | 1.5 [0.1–3.3] |
Comorbiditiesa, n (%) | |
0 | 10 (33.3) |
≥ 1 | 20 (66.7) |
Primary site of infection, n (%) | |
Abdominal | 9 (30) |
UTI | 6 (20) |
SST | 4 (13) |
Others | 11 (37) |
Type of primary infection, n (%) | |
Community acquired | 13 (43) |
Hospital acquired | 17 (57) |
Documentation of infection, n (%) | |
Gram-negative | 7 (23.3) |
Gram-positive | 6 (20) |
Virus | 1 (3.3) |
Co-infection | 6 (20) |
Non-documented infection | 10 (33.3) |
Hydrocortisone, n (%) | 10 (33) |
Day 3–4 data | |
Immunology | |
Median mHLA-DR, Ab/C [IQR] | 7348 [3838–10103] |
Median TNFα secretion post-LPS stimulation, pg/mL [IQR] | 701 [320–1260] |
Outcomes | |
Vasopressor requirement, n (%) | 30 (100) |
Median vasopressor duration, days [IQR] | 3.5 [2–6.8] |
Hemofiltration, n (%) | 10 (33) |
Mechanical ventilation, n (%) | 22 (73) |
Median ICU length of stay, days [IQR] | 8 [4.2–12] |
Median hospital length of stay, days [IQR] | 56 [20–78] |
Mortality at day 28, n (%) | 4 (13.3) |
