Figure 3 | Scientific Reports

Figure 3

From: Bacteria-induced expression of the pig-derived protegrin-1 transgene specifically in the respiratory tract of mice enhances resistance to airway bacterial infection

Figure 3

Characterization of transgene expression in transgenic mice from line 438. (A) Expression of EGFP marker gene in transgenic offspring from line 438. (B) Relative expression levels of PG-1 mRNA in the trachea, lung, heart, muscle, liver, brain, and skin tissues of line 438 transgenic mice with or without LPS treatment. (C) Relative expression levels of PG-1 mRNA in the trachea, lung, heart, muscle, liver, brain, and skin tissues of line 438 transgenic mice with or without A.pp infection. A.pp infection group’s tissue values labeled with a “*” means they are significantly different from the corresponding tissue value in no A.pp infection group. (D) PG-1 protein levels in the trachea and lung tissues of line 438 transgenic mice injected with LPS. Four transgenic mice were analyzed in B and C, and data shown are means ± SEMs.

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