Figure 4

Analysis of resistance of PG-1 transgenic mice to nasal A.pp infection. (A) Valuation of susceptibility of WT mice to A.pp infection by nasal inoculation of the different A.pp dosages. Infected mice were monitored for 8 days (192 h) to calculate death rate. (B) Comparison of death rate between line 438 transgenic mice and their WT littermates after nasal inoculation of A.pp at 6.555 × 107 CFU per mouse. *Mean difference between two groups reaches level of significance at P < 0.05.