Table 1 Effect of immersion time of magnesium oxide tablets into food thickeners on the disintegration time (Magmitt Tab.)

From: Appropriate usage of food thickening agents to prevent non-disintegration of magnesium oxide tablets

 

Immersion time

Disintegration time (s)

Number of non-disintegrating tablets

Range

Mean

Food thickeners

No immersion

4–7

5.1 ± 1.2

0

Tsururinko Quickly

1 min

4–9

5.5 ± 1.7

0

10 min

12– > 7200

1590.0 ± 2917.1

2

30 min

1260– > 7200

4109.5 ± 2152.1***

2

Hightoromeal

1 min

113–1520

889.3 ± 532.6

0

10 min

65– > 7200

2744 ± 2419.3**

1

30 min

100– > 7200

4145 ± 2781.8***

4

Neo-Hightoromeal III

1 min

4–55

9.8 ± 14.4

0

10 min

13– > 7200

750.3 ± 2043.5

1

30 min

300– > 7200

4460.8 ± 2794.8***

4

  1. Disintegration test was performed using first fluid (pH 1.2).
  2. **P < 0.01 and ***P < 0.001 represent significant differences (compared to non-immersing tablet).