Figure 2 | Scientific Reports

Figure 2

From: Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms

Figure 2

Cell viability (A), GSH levels (B) and ROS production (C). Panel (A): MCF-7, HepG2 and Fibroblasts cells were incubated with vehicle (0) or fruti at 15.2, 31.2, 62.5, 125 and 250 µM for 24 h. Panel (B): For GSH measurement MCF-7 cells were incubated with vehicle (0) or fruti at 12.5, 25, 50 and 100 µM for 0.5, 2, 16 and 24 h. Panel (C): ROS levels were monitored in MCF-7 cells loaded with DCFH-DA that were incubated with vehicle (0) or fruti (25, 50, 75 and 100 µM) for 60 min. Results are expressed as mean ± S.E.M. (n = 3) and were analyzed by one-way ANOVA followed by Newman Keuls post hoc test. *p < 0.05 when compared to vehicle group.

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