Figure 3 | Scientific Reports

Figure 3

From: Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms

Figure 3

Gene expression of CCND1, BCL-2 and VEGFA in MCF-7 (A), HepG2 (B) and fibroblasts (C) and proteins levels in MCF-7 (D, E, F). Panel (A), (B) and (C): CCND1, BLC-2 and VEGFA expression in MCF-7, HepG2 and Fibroblasts cells, respectively; Panel (D), (E) and (F): CCND1, BCL-2 and VEGFA proteins levels in MCF-7 cells by Western blot assay. The blot images have been cropped for conciseness. The full-size blots are presented in Supplementary Fig. S2. Cells were incubated with vehicle (0) or fruti 10, 25 and 50 µM for 24 h. Results are expressed as mean ± S.E.M. (n = 4–6) and were analyzed by one-way ANOVA followed by Newman Keuls post hoc test. *p < 0.05 when compared to vehicle group.

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