Figure 5
NF-kB1 gene expression (Panel A) and protein levels of pJNK (Panel B), pSTAT3 and STAT3 (Panel C) in MCF-7 cells. For pJNK and NF-κB1 analysis, cells were incubated with vehicle (0) or fruti at 10, 25 and 50 µM for 24 h. For pSTAT3 and STAT3 analysis, cells were incubated with vehicle (0) or fruti at 50 µM in the presence or absence of IL-6 (100 ng ml−1) for 15 until 90 min. The blot images have been cropped for conciseness. The full-size blots are presented in Supplementary Fig. S6. Results are expressed as mean ± S.E.M. (n = 3) and were analyzed by one-way ANOVA followed by Newman Keuls post hoc test. * p < 0.05 when compared to vehicle group.
