Figure 3

Humoral immune response to COVID-19. Serum samples from healthy controls (n = 125) or COVID-19 patients collected during the 1st week (n = 10), 2nd week (n = 23), 3rd week (n = 14), or 4th week (n = 5) of symptoms-onset were tested for IgG and IgM against SARS-CoV-2 S1 (a,b) and N (c,d) proteins using the developed ELISA. The dotted lines represent the cut-off of each assay. Correlation of S1 IgG (e), S1 IgM (f), N IgG (g) and N IgM (h) with days after symptom onset. Comparison of IgM and IgG for each patient based on the time of collection for S1 antibodies (i) and N antibodies (j).