Table 5 Univariate survival analysis for ocular melanoma treated with curative intent.
From: Clinical features and survival outcomes of ocular melanoma in a multi-ethnic Asian cohort
Characteristic | Recurrence-free survival | Overall survival | |||
|---|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | ||
Sex | Female | Referent | 0.163 | Referent | 0.181 |
Male | 0.49 (0.18, 1.33) | 0.40 (0.10, 1.53) | |||
Age at diagnosis (years) | ≤ 40 | Referent | 0.276 | Referent | 0.117 |
> 40 | 1.76 (0.64, 4.84) | 2.99 (0.76,11.79) | |||
ECOG performance status | 0 | Referent | 0.945 | Referent | 0.696 |
1–3 | 0.96 (0.26 to 3.43) | 1.42 (0.24, 8.25) | |||
History of smoking | No | Referent | 0.032 | Referent | 0.167 |
Yes | 0.29 (0.09, 0.90) | 0.35 (0.08, 1.55) | |||
Symptoms at presentation | Absent | Referent | 0.087 | Referent | 0.143 |
Present | 2.52 (0.87, 7.27) | 2.88 (0.70, 11.82) | |||
Tumour site | Conjunctiva | Referent | 0.686 | Referent | 0.986 |
Uvea | 0.77 (0.22, 2.69) | 0.99 (0.19, 5.02) | |||
Pigmentation | Low | Referent | 0.031 | Referent | 0.510 |
High | 3.27 (1.12, 9.59) | 1.60 (0.40, 6.43) | |||
Histological type | Non-epithelioid | Referent | 0.245 | Referent | 0.549 |
Epithelioid | 1.80 (0.67, 4.84) | 1.51 (0.40, 5.73) | |||
AJCC staging | T1–2 | Referent | 0.021 | Referent | 0.016 |
T3–4 | 3.81 (1.23, 11.83) | 6.56 (1.42, 30.35) | |||