Table 5 Univariate survival analysis for ocular melanoma treated with curative intent.

From: Clinical features and survival outcomes of ocular melanoma in a multi-ethnic Asian cohort

Characteristic

Recurrence-free survival

Overall survival

HR (95% CI)

p

HR (95% CI)

p

Sex

Female

Referent

0.163

Referent

0.181

Male

0.49 (0.18, 1.33)

0.40 (0.10, 1.53)

Age at diagnosis (years)

 ≤ 40

Referent

0.276

Referent

0.117

 > 40

1.76 (0.64, 4.84)

2.99 (0.76,11.79)

ECOG performance status

0

Referent

0.945

Referent

0.696

1–3

0.96 (0.26 to 3.43)

1.42 (0.24, 8.25)

History of smoking

No

Referent

0.032

Referent

0.167

Yes

0.29 (0.09, 0.90)

0.35 (0.08, 1.55)

Symptoms at presentation

Absent

Referent

0.087

Referent

0.143

Present

2.52 (0.87, 7.27)

2.88 (0.70, 11.82)

Tumour site

Conjunctiva

Referent

0.686

Referent

0.986

Uvea

0.77 (0.22, 2.69)

0.99 (0.19, 5.02)

Pigmentation

Low

Referent

0.031

Referent

0.510

High

3.27 (1.12, 9.59)

1.60 (0.40, 6.43)

Histological type

Non-epithelioid

Referent

0.245

Referent

0.549

Epithelioid

1.80 (0.67, 4.84)

 

1.51 (0.40, 5.73)

 

AJCC staging

T1–2

Referent

0.021

Referent

0.016

T3–4

3.81 (1.23, 11.83)

6.56 (1.42, 30.35)