Figure 1 | Scientific Reports

Figure 1

From: The liposomal delivery of hydrophobic oxidovanadium complexes imparts highly effective cytotoxicity and differentiating capacity in neuroblastoma tumour cells

Figure 1

Structures and cytotoxicity of oxidovanadium complexes. (A) Structures of oxidovanadium complexes. AL1 has a diamine bis (phenolato) tetradentate ligand (a salan), AL2–4 have aminoalcohol bisphenol ligands, and all have coordinated V(IV) ions. AL1–4 are highly water insoluble. BMOV has maltolato ligands, a coordinated vanadium(V) ion and is water soluble. (B,C) cytotoxicity of oxidovanadium complexes in IMR32 and KELLY cells. IMR32 (B) and KELLY (C) cells were treated with increasing concentrations of oxidovanadium complexes up to 10 µM for BMOV and AL1,2,4 and up to 5 µM for AL3. After 3 days, cells were stained with Hoechst and nuclei were counted and normalised to ethanol-only treated cells (n = 3, SD shown).

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