Table 1 Clinical characteristics of the included COVID-19 patients.

From: High aspartate aminotransferase to alanine aminotransferase ratio on admission as risk factor for poor prognosis in COVID-19 patients

Characteristics

All patients (n = 567)

AST/ALT < 1.38 (n = 367)

AST/ALT ≥ 1.38 (n = 200)

P Value

Age, median (IQR), years

55 (37–67)

51 (37–64)

60 (37.3–71)

0.001*

Sex

0.278

Male

247 (43.6)

166 (45.2)

81 (40.5)

 

Female

320 (56.4)

201 (54.8)

119 (59.5)

 

Time

Illness onset to hospital admission, median (IQR), days

7 (4–10)

7 (4–10)

7 (3–9)

0.059

Signs and symptoms

Fever

455 (80.2)

293 (79.8)

162 (81)

0.74

Myalgia

143 (25.2)

79 (21.5)

64 (32)

0.006*

Fatigue

208 (36.7)

117 (31.9)

91 (45.5)

0.001*

Headache

36 (6.3)

22 (6)

14 (7)

0.639

Cough

370 (65.3)

238 (64.9)

132 (66)

0.784

Chest tightness

222 (39.2)

144 (39.2)

78 (39)

0.956

Chest pain

27 (4.8)

19 (5.2)

8 (4)

0.529

Diarrhea

51 (9)

33 (9)

18 (9)

0.997

Comorbidities

Any

250 (44.1)

154 (42)

96 (48)

0.166

COPD

36 (6.3)

17 (3)

19 (9.5)

0.023*

Hypertension

183 (32.3)

115 (31.3)

68 (34)

0.517

Diabetes

85 (15)

50 (13.6)

35 (17.5)

0.217

Cardiovascular disease

53 (9.3)

25 (6.8)

28 (14)

0.005*

Cerebrovascular disease

32 (5.6)

16 (4.4)

16 (8)

0.073

Chronic kidney disease

31 (5.5)

12 (3.3)

19 (9.5)

0.002*

 ≥ 2 comorbidities co-exist

108 (19)

58 (15.8)

50 (25)

0.008*

Outcomes

Recovery and discharge

490 (86.4)

336 (91.6)

154 (77)

 < 0.001*

Death

65 (11.5)

24 (6.5)

41 (20.5)

 < 0.001*

Transfer to specialized hospitals

12 (2.1)

7 (1.9)

5 (2.5)

0.87

  1. Values are numbers (percentages) unless stated otherwise.
  2. *A two-tailed P value less than 0.05 was considered statistically significant.