Table 4 Univariate and multivariate analysis on poor prognosis (Death).
Biochemical parameters | Univariate analysis | Selection process of variables | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
OR | P Value | VIF | Correlat coefficiention | P Value | OR | P Value | |
Liver | |||||||
AST/ALT | 3.62 (2.35–5.57) | < 0.001* | 1.5 | – | – | 99.9 (2.1–4280.5) | 0.02* |
Total bilirubin | 1.06 (1.02–1.11) | 0.004* | 1.2 | – | – | 0.99 (0.88–1.12) | 0.916 |
Kidney | |||||||
Blood urea nitrogen | 1.14 (1.09–1.19) | < 0.001* | 7.8 | 0.34 | < 0.001* | 1.64 (1.01–2.66) | 0.047* |
Creatinine | 1.002 (1.001–1.003) | < 0.001* | 8.2 | 0.25 | < 0.001* | – | – |
Heart | |||||||
Lactate dehydrogenase | 1.009 (1.006–1.011) | < 0.001* | 2.3 | – | – | 1.02 (1–1.03) | 0.05 |
Creatinine kinase | 1.001 (1–1.002) | 0.103 | – | – | – | – | – |
Creatine kinase–MB | 1.05 (1.01–1.09) | 0.006* | 1.3 | – | – | 0.79 (0.52–1.19) | 0.252 |
Blood | |||||||
White blood cell count | 1.17 (1.09–1.26) | < 0.001* | 18.7 | 0.11 | 0.01* | ||
Neutrophil count | 1.24 (1.15–1.34) | < 0.001* | 18.2 | 0.18 | < 0.001* | 0.66 (0.28–1.54) | 0.333 |
Lymphocyte count | 0.17 (0.08–0.34) | < 0.001* | 2.7 | – | – | 0.11 (0.04–2.78) | 0.181 |
Hemoglobin | 0.98 (0.97–0.99) | 0.002* | 1.2 | – | – | 0.94 (0.87–1.01) | 0.103 |
Platelet count | 0.99 (0.98–0.99) | < 0.001* | 1.6 | – | – | 1.01 (0.98–1.04) | 0.47 |
Microcirculation dysfunction | |||||||
Lactate | 2.3 (1.75–3) | < 0.001* | 1.3 | – | – | 30.53 (2.1–444.4) | 0.012* |
D-dimer | 1.02 (1–1.04) | 0.018* | 1.4 | – | – | 0.99 (0.95–1.03) | 0.493 |
Fibrinogen | 1.52 (1.14–2.03) | 0.004* | 1.7 | – | – | 1.46 (0.38–5.66) | 0.581 |
Systematic inflammation | |||||||
IL-6 | 1.04 (1.02–1.06) | < 0.001* | 1.5 | – | – | 1.05 (1–1.1) | 0.054 |
C-reactive protein | 1.26 (1.19–1.34) | < 0.001* | 2.7 | – | – | 0.92 (0.6–1.4) | 0.671 |
Procalcitonin | 69.6 (17.6–275.8) | < 0.001* | 2.3 | – | – | 0.33 (0.004–25.44) | 0.618 |
