Table 4 Reported adverse events with long-term golimumab treatment.

From: Real-life experience with 4 years of golimumab persistence in ulcerative colitis patients

Type of adverse event

N (%)

Infections

Respiratory: mild respiratory infections (3), tracheobronchitis (1), pneumonia (1a,b), pneumonitis (1), influenza (1)

15 (44.1%)

Urinary: urinary tract infections (5)

Gastrointestinal: acute gastroenteritis (1)

Otolaryngology (ENT): tonsillitis (1)

Others: mononucleosis (1b)

Skin process

Rash at the injection site (1), folliculitis (1), pruritus and urticaria (1), eczema-like rash with psoriatic distribution (2a), rash (1)

6 (17.6%)

Neurological processes

Myelitis (2a,b), headaches (2), dizziness (1)

5 (14.7%)

Arthropathies

Reactive knee arthritis (1a,b), arthralgia (1)

2 (5.8%)

Heart disease

Heart failure (1a,b)

1 (2.9%)

Others

Lupus-like condition (1a,b), leukopenia (1), fever (2a,b), bronchospasm (1)

5 (14.7%)

Total

34 (100%)

  1. Data are expressed as absolute number in each adverse event (n) and absolute number (%) in each type of adverse event.
  2. aAdverse event that caused golimumab discontinuation.
  3. bAdverse event that caused patient hospitalization.