Table 5 Univariate, bivariate results of female gender and started CD4 + T-Cell base value modeling and multivariate modeling and CD4 + T-Cell Base value simultaneously with other possible important covariates associated with CD4 + decline toward to HIV progression during study period.

From: The rapid CD4 + T-lymphocyte decline and human immunodeficiency virus progression in females compared to males

Analysis

Models

Variable

Statistical Analysis

n

Events % (n)

Censored % (n)

β(Beta)

SE(β)

[β/SE(β)]2

Sig. (P-Value)

HR (eβ)

95% CI for eβ

Univariate

Model-1

Gender:

178

67 (119)

33 (59)

 

1. Males

118

  

0

1

Referent

0

1

Referent

2. Females

60

  

0.343

0.194

3.114

0.0700

1.4

0.96, 2.06

Model-2

CD4 + T-Cell Base Value (in Hundreds)

178

67 (119)

33 (59)

− 0.255

0.066

14.674

0.0001

0.9

0.68, 0.88

Bivariate

Model-1

Gender:

178

67 (119)

33 (59)

1. Males

118

  

0

1

Referent

0

1

Referent

2. Females

60

  

0.352

0.194

3.279

0.0701

1.4

0.97, 2.08

CD4 + T-cell base value (in hundreds)

178

67 (119)

33 (59)

− 0.251

0.066

14.319

0.0002

0.8

0.68,0.88

Multivariate

Model-1

Gender:

178

69 (119)

33 (59)

1. Males

118

  

0

1

Referent

0

1

Referent

2. Females

60

  

0.657

0.223

8.628

0.0033

1.93

1.24, 2.99

CD4 + T-Cell Base Value (in Hundreds)

178

67 (119)

33 (59)

− 0.387

0.093

17.313

0.0001

0.7

0.56, 0.81

Gender & CD4 + T-Cell base value (in Hundreds) and other covariates* in study

178

67 (119)

33 (59)

0.281

0.117

5.779

0.0162

1.3

1.05, 1.66

  1. Sig., Significant; eβ, Hazard Ratio (HR); CI, Confidence Interval.
  2. Other Covariates*: clinical, hematology (Complete blood cell count (CBC)/Differential automated (Diff.), socio-demographic (supplemental Tables 1, 2) and socio-behavioral risk factors (supplemental Tables 3, 4) were used to control for possible confounding or interaction.