Table 6 Parameter estimates using Poisson and NB mixed-effects model.
From: Negative binomial mixed models for analyzing longitudinal CD4 count data
Covariates | Negative binomial mixed-effects model | Poisson mixed-effects model | |||||
---|---|---|---|---|---|---|---|
Estimate | SE | Pr >|t| | 95% CI for NB estimate | Estimate | SE | Pr >|t| | |
Intercept | 6.4697 | 0.04982 | < 0.0001 | (6.3715, 6.5679) | 6.4625 | 0.04264 | < 0.0001 |
Time in month | 0.007824 | 0.000989 | < 0.0001 | (0.005875, 0.009774) | 0.006564 | 0.001706 | 0.0002 |
Sqrt_Time | − 0.08649 | 0.009307 | < 0.0001 | (− 0.1048, − 0.06815) | − 0.06839 | 0.009830 | < 0.0001 |
ART initiation (post) | 0.2301 | 0.01238 | < 0.0001 | (0.2058, 0.2543) | 0.1947 | 0.002537 | < 0.0001 |
Baseline BMI category (ref. = normal weight) | |||||||
Obese | 0.4815 | 0.1113 | < 0.0001 | (0.2633, 0.6996) | 0.4985 | 0.1147 | < 0.0001 |
Overweight | 0.02561 | 0.04975 | 0.6067 | (− 0.07191, 0.1231) | 0.03131 | 0.05148 | 0.5431 |
Underweight | 0.005901 | 0.07927 | 0.9407 | (− 0.1495, 0.1613) | 0.01691 | 0.08264 | 0.8379 |
Baseline HIV viral load category (ref. = low VL) | |||||||
High VL | − 0.2393 | 0.05157 | < 0.0001 | (− 0.3404, − 0.1382) | − 0.3074 | 0.05065 | < 0.0001 |
Medium VL | − 0.1258 | 0.04587 | 0.0061 | (− 0.2157, − 0.03585) | − 0.1121 | 0.04686 | 0.0168 |
Undetectable | 0.1377 | 0.2901 | 0.6351 | (− 0.4310, 0.7064) | 0.1199 | 0.2978 | 0.6872 |
Number of sexual partners (ref. = stable partner) | |||||||
Many partners | − 0.1560 | 0.09394 | 0.0967 | (− 0.3402, 0.02811) | − 0.1674 | 0.09908 | 0.0911 |
No partner | − 0.04821 | 0.04993 | 0.3343 | (− 0.1461, 0.04967) | − 0.05913 | 0.05164 | 0.2522 |
Age group in years (ref. = < 20) | |||||||
20–29 | 0.01166 | 0.03104 | 0.7072 | (− 0.04919, 0.07251) | − 0.00791 | 0.007830 | 0.3125 |
30–39 | 0.02852 | 0.03432 | 0.4060 | (− 0.03876, 0.09580) | − 0.01239 | 0.008474 | 0.1438 |
40–49 | − 0.00719 | 0.04545 | 0.8743 | (− 0.09629, 0.08191) | − 0.03422 | 0.01112 | 0.0021 |
50–59 | − 0.05694 | 0.06662 | 0.3927 | (− 0.1875, 0.07365) | − 0.1399 | 0.01549 | < 0.0001 |
≥ 60 | 0.2082 | 0.1532 | 0.1741 | (− 0.09205, 0.5084) | − 0.3107 | 0.03519 | < 0.0001 |
Education attainment (ref. = secondary or high school) | |||||||
Primary school | − 0.04509 | 0.09084 | 0.6196 | (− 0.2232, 0.1330) | − 0.03582 | 0.09263 | 0.6990 |
Residence of participant (ref. = urban) | |||||||
Rural | − 0.00373 | 0.03947 | 0.9246 | (− 0.08112, 0.07365) | 0.01337 | 0.04038 | 0.7406 |