Table 3 Differentially expressed known and novel micro RNAs (miRNAs) between high and low-RFI animals within each breed population [Angus, Charolais, and Kinsella Composite (KC)], with a differential expression threshold of P-value < 0.05 and Fold-change (FC)  > 1.5.

From: Bovine hepatic miRNAome profiling and differential miRNA expression analyses between beef steers with divergent feed efficiency phenotypes

Angus

MicroRNA

logCPM

LR

logFC

P-value

Known

bta-miR-11985

1.621

13.815

− 1.377

2.02E−04**

bta-miR-2285bg

1.137

8.352

1.185

3.85E−03

bta-miR-2285n

1.387

8.151

1.082

4.30E−03

bta-miR-2285u

2.058

7.091

0.836

7.75E−03

bta-miR-424-3p

1.518

6.951

0.959

8.38E−03

bta-miR-27a-5p

1.221

5.840

− 0.978

0.016

bta-miR-24

1.242

5.788

− 0.967

0.016

bta-miR-507b

1.399

5.536

− 0.9

0.019

bta-miR-449a

1.701

5.152

0.782

0.023

bta-miR-133b

2.064

4.528

0.663

0.033

Novel

bta-miR-AB-2

13.325

14.568

− 0.833

1.35E−04**

bta-miR-AB-47

12.173

6.063

0.617

0.014

Charolais

Known

bta-mir-2415-3p

3.608

29.032

1.261

7.12E−08**

bta-mir-2419-5p

6.405

24.192

0.797

8.72E−07**

bta-mir-2285i

1.906

9.603

1.117

0.002

bta-mir-133a

5.218

9.457

− 0.966

0.002

bta-mir-449a

1.456

9.648

0.64

0.002

bta-mir-2346

0.871

8.829

− 1.33

0.003

bta-mir-1842

1.058

6.220

− 1.026

0.013

bta-mir-2284ac

2.414

6.068

0.656

0.014

bta-mir-2285ai-5p

2.442

5.946

0.645

0.015

bta-mir-12001

1.884

5.527

− 0.729

0.019

bta-mir-299

1.565

5.103

0.772

0.024

bta-mir-2284c

0.490

4.773

− 1.104

0.029

bta-mir-485

0.816

3.860

0.747

0.043

bta-mir-6521

1.445

3.855

− 0.872

0.049

bta-mir-365-5p

1.320

4.076

0.916

0.049

bta-mir-7859

0.659

3.860

0.696

0.0496

Novel

bta-miR-AB-2

13.410

10.823

0.77

0.001**

bta-miR-AB-15

11.255

5.830

0.735

0.0158

KC

Known

bta-miR-190a

1.873

77.302

− 3.133

1.47E−18**

bta-miR-449a

2.225

20.035

1.252

7.61E−06**

bta-miR-155

6.653

17.100

0.829

3.55E−05**

bta-miR-424-5p

4.561

12.718

0.756

3.62E−04**

bta-miR-223

5.207

12.131

0.737

4.96E−04**

bta-miR-1246

4.554

10.385

− 0.683

1.27E−03

bta-miR-363

1.947

8.661

0.866

0.003

bta-miR-147

2.006

7.647

0.801

0.006

bta-miR-2411-3p

1.834

5.032

− 0.677

0.025

bta-miR-2483-5p

0.672

4.255

0.877

0.039

Novel

bta-miR-AB-63

16.176

77.900

− 0.864

9.58E−04**

bta-miR-AB-225

14.839

5.533

1.228

0.002

bta-miR-AB-2

11.531

4.147

− 0.677

0.013

  1. The sign of logFC shows the direction of miRNA expression in low-RFI steers relative to high-RFI animals. The miRNAs that were significantly differentially expressed at a more stringent threshold of Bonferroni false discovery rate (FDR) correction < 0.05 and Fold-change > 1.5 are highlighted in bold and a “**” was added to their P-values. logCPM = log2 (counts per million), LR = likelihood ratio test static value, and logFC = log2(Fold-change).
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