Table 3 Comparison of the Linear Regression (LR) using Standard Least Squares method, Generalized Regression (GR) model using a logarithmic transformation and the double-lasso method, and the main ablation experiments of the Artificial Neural Network (ANN) methods tried.

From: Area under the expiratory flow-volume curve: predicted values by artificial neural networks

# Layers

# Hidden nodes

Activation functions

R2

Root Mean Square Error (RMSE)

Mean absolute deviance

Average processing time (s)

Sigmoidal

Gaussian

Linear

Train

Test

Valid

Train

Test

Valid

Train

Test

Valid

 

1 (LR)

0

   

0.731

0.739

0.770

3.107

3.062

2.928

0.040

− 0.243

− 0.157

1

1 (GR)

0

   

0.757

0.770

0.783

3.261

3.174

3.155

− 0.229

0.035

− 0.993

1

2**

0

2

2

2

0.794

0.780

0.822

3.174

3.221

3.088

2.195

2.308

2.123

100

2*

2*

2*

0.809

0.787

0.831

3.117

3.192

3.038

2.117

2.273

2.070

240

4

4

4

0.814

0.784

0.824

3.102

3.269

3.092

2.088

2.289

2.114

120

4*

4*

4*

0.813

0.789

0.832

3.097

3.196

3.031

2.092

3.196

3.031

660

6

6

6

0.818

0.789

0.824

3.065

3.178

3.083

2.066

2.262

2.117

150

6*

6*

6*

0.818

0.797

0.830

3.066

3.144

3.022

2.066

2.222

2.075

1800

3**

6

2

2

2

0.798

0.785

0.822

3.147

3.214

3.091

2.177

2.285

2.126

75

12

4

4

4

0.810

0.790

0.832

3.088

3.193

3.030

2.110

2.256

2.065

90

18

6

6

6

0.828

0.797

0.824

3.010

3.165

3.115

2.005

2.217

2.217

180

  1. The ablation study identified the 2 hidden-layer ANN design (i.e., each layer with three sigmodal, three linear and three Gaussian activation functions) as the best compromise between improved performance and processing speed (bold characters).
  2. *Using an additive sequence of 100 models based on a learning rate of 0.1.
  3. **Using for optimization a robust fit with a squared penalty method and transformed covariates.