Table 4 Comparison between patients with and without somatic mutation.
Number Mean | Without G > A mutation | With G > A mutation | P-value |
|---|---|---|---|
Age (years) | |||
≤ 55 | 12 (36.4) | 15 (60.0) | 0.111 |
> 55 | 21 (63.6) | 10 (40.0) | |
Sex | |||
F | 10 (30.3) | 12 (48.0) | 0.186 |
M | 23 (69.7) | 13 (52.0) | |
Location | |||
Ascending | 17 (51.5) | 9 (36.0) | 0.500 |
Transverse | 2 (6.06) | 2 (8.0) | |
Descending | 14 (42.4) | 14 (56.0) | |
Type | |||
Adeno | 16 (48.4) | 23 (92.0) | 0.006 |
Muci | 7 (21.2) | 1 (4.0) | |
Signet | 5 (15.1) | 1 (4.0) | |
Undif | 5 (15.1) | 0 (0.0) | |
Grade | |||
G1 | 4 (12.1) | 4 (16.0) | 0.097 |
G2 | 15 (45.4) | 17 (68.0) | |
G3 | 14 (42.4) | 4 (16.0) | |
Tumor size | |||
T1 | 3 (9.09) | 2 (8.0) | 0.622 |
T2 | 16 (48.4) | 12 (48.0) | |
T3 | 10 (30.3) | 5 (20.0) | |
T4 | 4 (12.12) | 6 (24.0) | |
LN invasion | |||
N0 | 14 (42.42) | 11 (44.0) | 0.877 |
N1 | 12 (36.36) | 10 (40.0) | |
N2 | 7 (21.21) | 4 (16.0) | |
Metastasis | |||
M0 | 27 (81.82) | 20 (80.0 | 0.861 |
M1 | 6 (18.18) | 5 (20.0) | |
LVI | |||
No | 21 (63.64) | 15 (60.0) | 0.792 |
Yes | 12 (36.36) | 10 (40.0) | |
Dukes* | |||
A | 10 (30.3) | 4 (16.0) | 0.599 |
B | 4 (12.12) | 5 (20.0) | |
C | 13 (39.39) | 11 (44.0) | |
D | 6 (18.18) | 5 (20.0) | |
Relapse | |||
No | 22 (68.75) | 15 (60.0) | 0.580 |
Yes | 10 (31.25) | 10 (4000) | |
Died | |||
No | 12 (38.71) | 6 (24.0) | 0.267 |
Yes | 19 (61.29) | 19 (76.0) | |
DFS (months) | 39.12 ± 12.19 | 48.16 ± 9.40 | 0.003 |
≥ 48 | 9 (27.27) | 18 (72.0) | 0.001 |
< 48 | 24 (72.73) | 7 (28.0) | |
OS (months) | 42.73 ± 11.51 | 54.40 ± 8.20 | < 0.001 |
≥ 48 | 12 (36.36) | 22 (88.0) | < 0.001 |
< 48 | 21 (63.64) | 3 (12.0) | |
MIR34A expression | 3.23 ± 1.02 | 3.15 ± 1.23 | 0.788 |
