Table 1 a: Patient characteristics, perioperative details and postoperative outcomes measured, b. Perioperative administration of fluids, blood products and inotropic and vasopressor medications.

From: Perioperative factors associated with postoperative morbidity after emergency laparotomy: a retrospective analysis in a university teaching hospital

Factor of interest

N (%)

Mean ± SD or median [IQR]

(a)

Gender (M: F)

47:39

 

Age

 

63.0 ± 15.8

Cardiac risk factors (Lee Revised Cardiac Index)

0 factors

26

 

1 factors

22

 

2 factors

18

 

3 factors

16

 

4 factors

4

 

Severity of pre-existing respiratory symptoms:

No symptoms

53

 

Dyspnoea on exertion

23

 

Dyspnea at rest

10

 

American Society of Anesthesiologists (ASA) Score

ASA 1

4

 

ASA 2

22

 

ASA 3

42

 

ASA 4

16

 

ASA 5

2

 

Initial SAP (mmHg)

 

118 ± 29

Initial DAP (mmHg)

 

58 ± 17

Initial MAP (mmHg)

 

80 ± 19

Initial HR (beats per minute)

 

93 ± 18

Intraoperative SAP (mmHg)

 

109 ± 14

Intraoperative DAP (mmHg)

 

57 ± 7

Intraoperative MAP (mmHg)

 

75 ± 8

Intraoperative HR (beats per min)

 

86 ± 16

Lowest intraoperative SAP (mmHg)

 

72 ± 12

Lowest intraoperative MAP (mmHg)

 

51 ± 9

Total intraoperative urine output (mls)

 

497 ± 445

Postoperative Transfusion

17 [20%]

 

Central venous access

69 (80%)

 

Arterial line

81 (94%)

 

Emergency category

Emergency

38

 

Urgent

48

 

Complexity of surgery

Major operation

37

 

Complex major operation

49

 

Number of surgeries during admission

1

41

 

2

42

 

3

3

 

Peritoneal soiling

Grade 1

43

 

Grade 2

12

 

Grade 3

10

 

Grade 4

21

 

Indication for surgery:

Intestinal obstruction

27

 

Enteric perforation

39

 

Gut ischaemia

14

 

Incarcerated hernia

4

 

Blunt trauma

2

 

Surgical procedure performed

Washout without resection

12

 

Total colectomy

7

 

Small bowel resection

22

 

Hartmann’s procedure

14

 

Delayed closure

2

 

Other procedures

29

 

Final Surgical pathology

Diverticular disease

8

 

Malignancy

10

 

Mesenteric ischaemia

18

 

Peptic ulcer disease

9

 

Adhesional obstruction

15

 

Incarcerated hernia

5

 

Toxic megacolon

1

 

NSAID induced colitis

1

 

Anastomotic leak

2

 

Other enteric perforation

4

 

Angiodysplasia

1

 

Intestinal obstruction

9

 

Colocutaneous fistula

1

 

Negative laparotomy

1

 

Latrogenic perforation during endoscopic procedure

1

 

Stage of cancer if applicable

Distant metastasis

4

 

Nodal metastasis

3

 

Primary tumour no spread

2

 

No malignancy/not applicable

77

 

CT performed preoperatively

76

 

CT reported preoperatively

60

 

Time to theatre (h)

 

2.5 [2.0–4.0]

Postoperative destination

ITU

25

 

HDU

43

 

Surgical ward

18

 

Unplanned return to theatre

9 [11%]

 

Unplanned critical care admission

20 [23%]

 

Critical care length of stay

4 [2–10.5]

 

30 day mortality

10 [12%]

 

90 day mortality

14 [16%]

 

Renal Replacement Therapy postoperatively

4 [5%]

 

Duration of Total Parenteral Nutrition (TPN) (days)

2.8 (6.8)

 

Medicine for the Elderly review postoperatively

15 [17%]

 

CCI score

 

27 [9–45]

Overall length of stay

 

14 [8–31]

Time of the day/week during which surgery was performed:

Daytime (0800–2000)

48

 

Night-time (2000–0800)

26

 

Weekend/public holiday daytime

12

 

Product

No of patients receiving product n

Mean total volume administered (mls) ± SD

(b)

Crystalloid

86

2041 ± 1317 mls

Colloid

14

Mean 110 + 330

RCC

23

190 ± 270

Fibrinogen

7

135 ± 45

Platelets

7

371 ± 183

Fresh frozen plasma (FFP)

10

760 ± 260

Noradrenaline

54

1.01 ± 0.90

Adrenaline

11

0.22 ± 0.17

Phenylephrine

32

310.9 ± 212

Metaraminol

39

2.3 ± 1.5

Ephedrine

7

8.6 ± 2.8

  1. NSAID = non steroidal anti inflammatory CT = computerized tomography scan, SAP = systolic arterial pressure, DAP = diastolic arterial pressure, MAP = mean arterial pressure, HR = heart rate, ITU = intensive treatment unit, HDU = high dependency unity.