Table 2 Beneficial effects of different phenolics detected in in vitro plants of N. jatamansi in UPLC-PDA analysis.

From: De novo transcriptome analysis of the critically endangered alpine Himalayan herb Nardostachys jatamansi reveals the biosynthesis pathway genes of tissue-specific secondary metabolites

S. no.

Compound name

Use in plant

Health benefits/accounts for

1

Gallic acid

Protection against UV and pathogens39

Cellular communication and signalling25

Anti-inflammatory, antimutagenic, antifungal, antiviral, anticancer and antioxidant activities40

2

Cinnamic acid

UV protectant and defence against pathogens39, lignification of cell wall41

Cellular communication and signalling25

Anticancer, antituberculosis,

antimalarial, antifungal, antimicrobial, antiatherogenic and antioxidant activities42

3

p-Coumaric acid

UV protectant and defence against pathogens39

Cellular communication and signalling25

Anti-melanogenic, anti-inflammatory, anti-cancerous activities43

4

Caffeic acid

UV protectant and defence against pathogens (insects, fungi and bacteria)39

Used for lignin synthesis leading to cell wall thickening

Cellular communication and signalling25

Antibacterial, antiviral, antioxidant, anti-inflammatory, anti-atherosclerotic, immunostimulatory, antidiabetic, cardioprotective, antiproliferative, hepatoprotective, anticancer and anti-hepatocellular carcinoma activities44

5

Ferulic acid

Component of primary cell wall, Cell wall rigidity

Cellular communication and signalling25

UV protectant and defence against pathogens39

Used in skin care products

Anti-inflammatory, antioxidant, antimicrobial, anticancer, and antidiabetic, anti-ageing activities45

6

Kaempferol

UV protectant and defence against pathogens46

Cellular communication and signalling

Anti-inflammatory, anti-tumour, anti-oxidant, cardiovascular, antidiabetic, hepatoprotective and neuroprotective effects47

7

Rutin

UV protectant and defence against pathogens48

Anti-inflammatory, antioxidant, cytoprotective, vasoprotective, anticarcinogenic, neuroprotective, antibacterial, antiprotozoal, antitumor, antiallergic, antiviral, vasoactive, cardioprotective, hypolipidaemic, antiplatelet, antispasmodic, and antihypertensive activities49,50