Table 1 Patients’ baseline characteristics.

From: Validation of Clinical Treatment Score post-5 years (CTS5) risk stratification in premenopausal breast cancer patients and Ki-67 labelling index

 

All patients (%)

Premenopausal

patients (%)

Postmenopausal

patients (%)

P value

Total

680 (100.0)

379 (55.7)

301 (44.3)

 

Age at diagnosis, median (range), years

50.3 (25–81)

43.5 (25–55)

58.8 (43–81)

 <.001

Tumor size, mm

   

.222

< 10

121 (17.8)

76 (20.1)

45 (15.0)

 

10–20

367 (54.0)

198 (52.2)

169 (56.1)

 

> 20

192 (28.2)

105 (27.7)

87 (28.9)

 

Pathologic nodal status

   

.736

None

463 (68.1)

265 (69.9)

198 (65.8)

 

1

107 (15.7)

55 (14.5)

52 (17.3)

 

2–3

62 (9.1)

35 (9.2)

27 (9.0)

 

4–9

35 (5.1)

18 (4.7)

17 (5.6)

 

> 9

13 (1.9)

6 (1.6)

7 (2.3)

 

Histologic grade

   

.002

Low

261 (38.4)

161 (42.5)

100 (33.2)

 

Intermediate

342 (50.3)

168 (44.3)

174 (57.8)

 

High

77 (11.3)

50 (13.2)

27 (9.0)

 

PR

   

 < .001

Negative

99 (14.6)

30 (7.9)

69 (22.9)

 

Positive

581 (85.4)

349 (92.1)

232 (77.1)

 

HER2

   

.572

Negative

552 (81.2)

313 (82.6)

239 (79.4)

 

Positive

79 (11.6)

41 (10.8)

38 (12.6)

 

Unknown

49 (7.2)

25 (6.6)

24 (8.0)

 

Ki-67 LI

   

.250

≤ 20%

562 (82.6)

308 (81.3)

254 (84.4)

 

> 20%

97 (14.3)

61 (16.1)

36 (12.0)

 

Unknown

21 (3.1)

10 (2.6)

11 (3.7)

 
  1. PR, progesterone receptor; HER2, human epidermal growth receptor 2; LI, labelling index.