Table 2 Association of HNF1B expression and clinicopathological characteristics, based on 93 cases of ccRCC.

Characteristic	Group	N	H-score mean	H-score median	p-value^a	Categorized H-score
Characteristic	Group	N	H-score mean	H-score median	p-value^a	Group 1	Group 2	Group 3	p-value^b
Gender					0.617				0.399
	Male	54	198.2	240		12	13	29
	Female	39	205.8	250		10	5	24
Age (mean = 63, median = 65)					0.849				0.414
	˂ 65	44	198.9	240		8	8	28
	≥ 65	49	203.5	260		14	10	25
pT classification					0.094				0.360
	pT1	70	212.4	265		15	11	44
	pT2	6	141.7	145		2	2	2
	pT3	17	177.1	170		5	5	7
Grade					0.002				0.012
	G1	22	255.5	300		2	2	18
	G2	53	196.1	240		14	9	30
	G3	13	167.7	170		3	6	4
	G4	5	106.0	50		3	1	1
Lymphovascular invasion*					0.264				0.558
	Yes	15	177.3	200		5	3	7
	No	75	207.1	260		16	14	45
Metastasis*					0.121				0.135
	Yes	10	158.0	140		3	4	3
	No	81	207.8	250		18	14	49
Recurrence*					0.458				0.899
	Yes	8	183.8	210		2	2	4
	No	83	204.1	250		19	16	48
rs4430796*					0.727				0.951
	Yes	31	207.7	270		6	2	21
	No	8	276.3	295		0	1	5
rs757210*					0.384				0.528
	Yes	36	216.1	275		0	0	3
	No	3	290.0	290		6	3	23

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