Table 2 List of genes related to cell process, disease, and functional class altered by DEP exposure.
Entity | Type | Relation | Gene |
|---|---|---|---|
Actin organization | Cell process | Regulation | DPYSL5, EPHA5, ERMN, ESR2, GJA1, IL1B, IL6, MAP1B, MEF2A, ROBO2 |
Apoptosis | Cell process | Regulation | ANKK1, CYP26B1, DCT, ESR2, GFRA4, GJA1, IFIT1, IL1B, IL6, MAP1B, MEF2A, ROBO2, THBS4 |
Axon guidance | Cell process | Regulation | CDH, DPYSL5, EPHA5, ESR2, MAP1B, ROBO2, SEMA4C |
Axonogenesis | Cell process | Regulation | CDH4, DPYSL5, EPHA5, IL6, MAP1B, MEF2A, ROBO2 |
Immune response | Cell process | Regulation | DCT, DPYSL5, ESR2, GJA1, IFIT1, IL1B, IL6, KCNA4, MEF2A, ROBO2 |
Inflammatory response | Cell process | Regulation | ESR2, GJA1, IL1B, IL6, MEF2A, THBS4 |
Nervous system development | Cell process | Regulation | CDH4, DPYSL5, EPHA5, ESR2, GJA1, IL1B, IL6, MAP1B, MEF2A, ROBO2, SEMA4C, SLC1A4, SYNPR, THBS4, TSKU |
Neurite outgrowth | Cell process | Regulation | CDH4, DPYSL5, ESR2, GFRA4, GJA1, IL1B, IL6, MAP1B, MEF2A, ROBO2, THBS4, TSKU |
Neurogenesis | Cell process | Regulation | CYP26B1, DPYSL5, EPHA5, ESR2, GJA1, MAP1B, MEF2A, ROBO2 |
Neuronal plasticity | Cell process | Regulation | EPHA5, ESR2, GJA1, IL1B, IL6, MAP1B, MEF2A, THBS4 |
Olfaction | Cell process | Regulation | CNGB1, ESR2 |
Oxidative stress | Cell process | Regulation | DCT, ESR2, GJA1, IL1B, IL6, MEF2A |
ROS generation | Cell process | Regulation | ESR2, GJA1, IL1B, IL6, MEF2A |
Sensory perception | Cell process | Regulation | ESR2, GJA1, IL6 |
Synaptic transmission | Cell process | Regulation | ESR2, GJA1, IL1B, IL6, KCNA4, MAP1B, MEF2A, SHANK1, SYNPR, THBS4 |
Synaptogenesis | Cell process | Regulation | EPHA5, ESR2, GJA1, IL1B, IL6, MAP1B, MEF2A, ROBO2, SHANK1, SYNPR, THBS4 |
Inflammation | Disease | Regulation | ESR2, GJA1, IL1B, IL6, THBS4 |
Neurodegeneration | Disease | Regulation | ESR2, IL1B, IL6, MAP1B |
Olfaction disorder | Disease | Genetic change | CNGB1 |
Quantitative change | CNGB1 | ||
Regulation | CNGB1 | ||
Olfactory receptor | Functional class | Expression | CYP26B1, DPYSL5, EPHA5, ESR2, GJA1, MAP1B, MEF2A, ROBO2 |
Promoter binding | MEF2A |
