Figure 6

WE but not PGG strongly inhibits NF-κB and IRF signaling pathways. BMDMs were pretreated with water extract (0.25, 0.5, or 2.5%) or PGG (10, 50, or 100 μM) for 2 h. Activation of cells with Pam3CSK4 stimulation for 1 h are shown by immunoblots using indicated antibodies. Full-length blots and markers are included in the Supplementary Fig. S2.