Figure 1

IL-1β up-regulated the mRNA expression level of MMP-3, MMP-13 and leptin, while simvastatin alleviated these phenomena. (A) MMP-3 mRNA expression levels of condylar chondrocytes treated with or without IL-1β and simvastatin. (B) MMP-13 mRNA expression levels of condylar chondrocytes treated with or without IL-1β and simvastatin. (C) Leptin mRNA expression level of condylar chondrocytes treated with or without IL-1β and simvastatin. *P < 0.05.