Figure 4 | Scientific Reports

Figure 4

From: Effect of high fat diet and excessive compressive mechanical force on pathologic changes of temporomandibular joint

Figure 4

Mechanical force induced TMJOA-like damages were exacerbated by high fat diet and alleviated by simvastatin. (A) The histological morphology of condylar cartilage of the mice in the eight different groups of ND, ND + ST, ND + MF, ND + MF + ST, HFD, HFD + ST, HFD + MF, HFD + MF + ST. (400 ×). (B) The cartilage thickness of different layers in the mice of the eight different groups (T total thickness, F fibrous layer, P proliferative layer, H hypertrophic layer). (C) The expression of inflammatory factor, IL-1β in the condylar cartilage of the mice in the eight different groups. (D) Immunohistochemical scores of IL-1β in the eight different groups. *P < 0.05; **P < 0.01.

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