Table 2 ROS disc properties of 129/SV-E wild-type (WT) and Prcd-KO mice across ages (P30 and P120).
From: Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes
Parameter value | Nanodomains of rhodopsin | Rhodopsin molecules | ||
|---|---|---|---|---|
Number | Density (µm2) | Number | Density (µm2) | |
P30 WT (n = 42) | 121 ± 75 | 183 ± 42 | 13,642 ± 8848 | 20,346 ± 4171 |
P120 WT (n = 47) | 118 ± 83 | 191 ± 64 | 13,857 ± 11,177 | 20,828 ± 4171 |
P30 Prcd-KO, regular (n = 61) | 106 ± 82 | 182 ± 44 | 12,089 ± 10,465 | 20,494 ± 4658 |
P30 Prcd-KO, irregular (n = 27) | 81 ± 59 | 158 ± 43 | 8582 ± 6621 | 16,059 ± 4276 |
P120 Prcd-KO, regular (n = 53) | 106 ± 98 | 167 ± 56 | 12,290 ± 11,434 | 18,345 ± 5297 |
P120 Prcd-KO, irregular (n = 48) | 67 ± 38 | 113 ± 47 | 8454 ± 5417 | 13,497 ± 3991 |
