Table 4 Molecular detection of the main opportunistic pathogenic species among women in this study.

From: Vaginal microbiota evaluation and prevalence of key pathogens in ecuadorian women: an epidemiologic analysis

 

Healthy microbiota

N (%)

Intermediate microbiota

N (%)

Bacterial vaginosis

N (%)

Aerobic vaginitis

N (%)

Candidiasis

N (%)

Coinfections

N (%)

Total

N (%)

P (X2)

Total incidence

276 (66.7)

43 (10.4)

23 (5.6)

49 (11.8)

7 (1.7)

16 (3.9)

414 (100.0)

 

Atopobium vaginae

Absence

179 (64.9)

21 (48.8)

9 (39.1)

29 (59.2)

1 (14.3)

4 (25.0)

243 (58.7)

0.001 (22.9)

Presence

97 (35.1)

22 (51.2)

14 (60.9)

20 (40.8)

6 (85.7)

12 (75.0)

171 (41.3)

Adjusted P-value

0.000***

0.198

0.075

0.941

0.032*

0.015*

  

Mobiluncus mulieris

Absence

275 (99.6)

42 (97.7)

19 (82.6)

45 (91.8)

7 (100.0)

13 (81.3)

401 (96.9)

0.001 (39.6)

Presence

1 (0.4)

1 (2.3)

4 (17.4)

4 (8.2)

0 (0.0)

3 (18.8)

13 (3.1)

Adjusted P-value

0.000***

0.746

0.000***

0.048*

0.746

0.000***

  

Gardnerella spp.

Absence

181 (65.6)

20 (46.5)

5 (21.7)

28 (57.1)

2 (28.6)

5 (31.3)

241 (58.2)

0.001 (28.5)

Presence

95 (34.4)

23 (53.5)

18 (78.3)

21 (42.9)

5 (71.4)

11 (68.8)

173 (41.8)

Adjusted P-value

0.000***

0.131

0.000***

0.872

0.131

0.052

  

Escherichia coli

Absence

250 (90.6)

36 (83.7)

20 (87.0)

37 (75.5)

5 (71.4)

15 (93.8)

363 (87.7)

0.038 (11.8)

Presence

26 (9.4)

7 (16.3)

3 (13.0)

12 (24.5)

2 (28.6)

1 (6.3)

51 (12.3)

Adjusted P-value

0.033*

0.541

0.913

0.033*

0.374

0.541

  

Enterococcus faecalis

Absence

273 (98.9)

41 (95.3)

22 (95.7)

48 (98.0)

7 (100.0)

16 (100.0)

407 (98.3)

0.510 (4.3)

Presence

3 (1.1)

2 (4.7)

1 (4.3)

1 (2.0)

0 (0.0)

0 (0.0)

7 (1.7)

Adjusted P-value

0.534

0.534

0.618

0.840

0.840

0.840

  

Candida albicans

Absence

275 (99.6)

41 (95.3)

22 (95.7)

49 (100.0)

5 (71.4)

15 (93.8)

407 (98.3)

0.001 (39.5)

Presence

1 (0.4)

2 (4.7)

1 (4.3)

0 (0.0)

2 (28.6)

1 (6.3)

7 (1.7)

Adjusted P-value

0.009**

0.224

0.328

0.328

0.000***

0.224

  
  1. N number of women who responded in the survey within each category; % assigned percentage for each classification within each category. The Chi-square test (P (X2) was used to evaluate statistical differences of the presence of each opportunistic pathogen against its absence in each type of vaginal microbiota. A value of P < 0.05 and 95% confidence intervals were considered significant for the test: *P ≤ 0.05; **P ≤ 0.01.; ***P ≤ 0.001. All initial values of P < 0.05 obtained by Chi-square analyses were then evaluated through Benjamini–Hochberg (BH) adjustment to detect false discovery rate (FDR) for conducting multiple comparisons. These P-values evaluated by BH adjustment were illustrated in the table as adjusted P-values.
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