Figure 3
From: Association of advanced glycation end products with sarcopenia and frailty in chronic kidney disease
Morphological analysis of gastrocnemius muscles. (A) HE staining of the gastrocnemius muscles. × 20 magnification. a, Sham mice; b, 5/6Nx mice; c, 5/6Nx mice treated with control-aptamer; d, 5/6Nx mice treated with AGE-aptamer. (B) Histograms representing the size distribution of skeletal muscle fibers. (C) Coefficient of variation in fiber size. n = 3 per each group. ††p < 0.01 compared with sham mice. ‡‡p < 0.01 compared with 5/6Nx mice plus control-aptamer.
