Table 4 Logistic regressions: likelihood of having diabetes.

From: Risk factors for type 1 diabetes, including environmental, behavioural and gut microbial factors: a case–control study

 

Likelihood of having diabetes

 

OR

95% IC

p-value

Adj p-value

Socio-demographic factors

Age at recruitment

1.15

0.89—1.49

0.290

0.6195

Gender (female)

1.07

0.43—2.61

0.879

0.925

Percentile BMI

0.99

0.98—1.003

0.179

0.507

BMI categories

Underweight

0.39

0.034—4.61

0.461

0.7785

Overweight

0.25

0.02—3.34

0.295

0.6195

Obese

0.36

0.02—5.11

0.448

0.779

Residency (rural)

0.96

0.39—2.32

0.924

0.925

The child consumes meals at school

0.51

0.19—1.40

0.193

0.507

The child consumes meals at home more than two times a week

0.42

0.17—1.07

0.070

0.2555

Sport activity

1.23

0.51—2.95

0.641

0.785

Having siblings

0.75

0.28—1.99

0.563

0.785

Having done regular health check-up

0.37

0.15—0.93

0.036

0.252

Use of antibiotics in the first two years of life

0.74

0.31—1.75

0.503

0.7785

Breastfeeding

0.68

0.22—2.14

0.519

0.7785

Weaning age (months)

0.68

0.46—1.03

0.068

0.2555

Presence of dogs and/or cats in the house

0.95

0.37—2.44

0.925

0.925

Mother age at recruitment

0.98

0.91—1.06

0.673

0.785

Mother education (at least high school)

0.34

0.14—0.83

0.018

0.189

Father age at recruitment

1.01

0.95—1.08

0.671

0.785

Father education (at least high school)

0.33

0.14—0.77

0.011

0.189

Important changes in the family contest in the last year

3.68

0.88—15.22

0.073

0.2555

Nutritional anamnesis

 

Total caloric intake (Kcal/die)

1.0023

1.0009—1.0036

0.001

0.005

Total supply of proteins (g)

1.06

1.02—1.10

0.002

0.007

Total supply of lipids (g)

1.03

1.002—1.069

0.036

0.072

Total supply of carbohydrates (g)

1.01

1.005—1.022

0.001

0.005

Total supply of CHO RA (g)

1.03

1.007—1.045

0.006

0.015

The child consumes more than two extra meals

1.67

0.73—3.82

0.224

0.329

The child consumes meals while watching TV

0.58

0.24—1.40

0.230

0.329

The child consumes sweets more than three times a week

1.08

0.47—2.47

0.859

0.859

Child family consumes meals all together

0.54

0.15—1.91

0.339

0.4238

The child often asks for supplementary portions of food

1.44

0.62—3.28

0.389

0.432

Microbiota

 

Akkermansia muciniphila (Log gene copies/g stool)

0.84

0.62—1.14

0.260

0.423

Bacteroides spp. (Log gene copies/g stool)

0.79

0.50—1.25

0.317

0.443

Bacteroidetes (Log gene copies/g stool)

0.28

0.15—0.51

0.000

0.000

Total bacteria Probe (Log gene copies/g stool)

0.72

0.46—1.12

0.147

0.318

Total bacteria SYBR (Log gene copies/g stool)

0.69

0.37—1.31

0.259

0.423

Firmicutes (Log gene copies/g stool)

7.49

3.25—17.28

0.000

0.000

Bifidobacterium spp. (Log gene copies/g stool)

0.20

0.10—0.38

0.000

0.000

Methanobrevibacter smithii 16S (Log gene copies/g stool)

0.97

0.73—1.30

0.858

0.930

Methanobrevibacter smithii Nihf (Log gene copies/g stool)

1.04

0.75—1.44

0.824

0.930

Simpson index

1.14

0.00005—23,610.2

0.980

0.980

Shannon index

0.51

0.13—2.03

0.341

0.443

Firmicutes/Bacteroidetes ratio

34,288.2

637.20—1,845,077

0.000

0.000

Margalef index

0.20

0.09—0.46

0.000

0.000

  1. The continuous variables are shown on a light grey background; the categorical variables are shown on a white background. Adj p-value: adjusted for multiple comparisons. Significant p-values are bolded.