Figure 1
(a) Representative illustration of minimal, intermediary, and maximal injury area in the striatum after microinjections directed to the germinal matrix of the right hemisphere. Adapted from53. Scale bar = 1 mm. (b) Number of newborn male rats in each experimental group showing injury in the ipsilateral striatum. Note more extensive lesions in groups microinjected with collagenase. (c) Values (mean ± standard deviation in mm2) for the area of the right striatum in the experimental groups (n = 5 in ANTAG, COL + ACTH, COL + ANTAG, and COL + ACTH + ANTAG groups; n = 6 in Control, ACTH, ACTH + ANTAG, and COL ones). Symbols represent individual values. *p < 0.05 for each comparison indicated. Note the control, collagenase and collagenase plus ACTH data. (d) Corresponding values (mean ± standard deviation in mm2) for the contralateral, left striatum. No statistically significant difference was found between groups.
