Figure 3

Phylogenetic tree of the LarAH groups. For each group whose activity is suspected the sequence logo is shown, with residues equivalent to D72, R75, H108, H174, F175, F176, K184, H200, I220, Y294, Q295, V297, K298, T353, P355, D356, W358, T359, A360, I362 of LarA (Table S3). Inside each logo, residues involved in catalytic activity are green, those involved in NPN binding are blue, those probably involved in substrate recognition are yellow, conserved residues differing from LarA are red, and those not conserved within the group are black. The logos were generated using Weblogo²¹. The groups for which at least one member have shown enzymatic activity are colored plain, the groups whose activity is suspected are striped black. The groups for which no activity was shown or suspected are colored black.