Table 4 Postoperative outcomes stratified by perioperative intravenous fluids.

From: Perioperative fluids and complications after pancreatoduodenectomy within an enhanced recovery pathway

 

IV fluids POD 0 < 4400

n = 61

IV fluids POD 0 ≥ 4400

n = 103

p-value

Complications

Overall, n (%)

47 (77)

97 (94)

0.001

Major (IIIa–IVb), n (%)

24 (39)

46 (45)

0.506

Minor (I–II), n (%)

23 (38)

51 (50)

0.149

Mortality 90 days after surgery, n (%)

2 (3)

2 (2)

0.629

CCI, median (IQR)

26.2 (4.4–38.4)

33.7 (20.9–47.3)

0.041

 Pulmonary complications, n (%)

10 (16)

32(31)

0.037

 Infectious complications, n (%)

20 (33)

48 (47))

0.083

 Cardio-vascular dysfunction, n (%)

8 (13)

10 (10)

0.500

 Renal failure, n (%)

2 (3)

5 (5)

0.322

Pancreas specific complications

Delayed gastric emptying, n (%)

31 (51)

49 (48)

0.810

 Grade A, n (%)

15 (25)

29 (28)

0.716

 Grade B, n (%)

8 (13)

13 (13)

1.000

 Grade C, n (%)

8 (13)

7 (7)

0.261

Pancreatic fistula (Grade B-C), n (%)

11 (18)

25 (24)

0.436

Biliary fistula n (%)

3 (5)

6 (6)

1.000

Postoperative hemorrhage, n (%)

11 (18)

16 (16)

0.677

 Grade A, n (%)

4 (6)

2 (2)

0.196

 Grade B, n (%)

1 (2)

5 (5)

0.417

 Grade C, n (%)

6 (10)

8 (8)

0.573

Lengths of stay

   

Primary, median (IQR)

14 (11–23)

19 (14–27)

0.034

Intensive care unit, median (IQR)

0 (0–0)

0 (0–0)

0.779

Total, median (IQR)

15 (11–23)

19 (14–29)

0.015

  1. n number, CCI Comprehensive Complication Index, IQR interquartile range, ml milliliter.